Think about how man is connected to God, and through what part of himself. Think about how that part is affected when it spreads out everywhere. Nothing is more miserable than a soul that circles around all things, searching even the depths of the earth. It tries to guess what other people are thinking by watching for signs. Yet this soul doesn't realize something simple: it's enough for a person to focus completely on tending the spirit within himself, and to truly serve that spirit.
Consider with thyself how man, and by what part of his, is joined unto God, and how that part of man is affected, when it is said to be diffused. There is nothing more wretched than that soul, which in a kind of circuit compasseth all things, searching (as he saith) even the very depths of the earth; and by all signs and conjectures prying into the very thoughts of other men's souls; and yet of this, is not sensible, that it is sufficient for a man to apply himself wholly, and to confine all his thoughts and cares to the tendance of that spirit which is within him, and truly and really to serve him.